Air-Displacement Micropipette – Complete Guide
What is an Air-Displacement Micropipette?
An air-displacement micropipette is a piston-driven laboratory instrument used to measure and transfer small liquid volumes (typically 0.1 µL to 1000 µL or more). It uses an air cushion between the piston and the liquid, which prevents direct contact between the internal mechanism and the sample.
These micropipettes are widely used in:
- Molecular biology laboratories
- Clinical diagnostics labs
- Pharmaceutical research
- Biotechnology laboratories
- Educational and research institutes
Working Principle
Air-displacement micropipettes operate using a piston that moves inside an airtight chamber.
Working steps:
- Press the plunger → Air inside the pipette is pushed out.
- Release the plunger → A vacuum is created inside the tip.
- Liquid enters the tip due to this vacuum.
- Press plunger again → Liquid is expelled from the tip.
This method provides high precision and repeatability, especially for aqueous solutions.
Main Parts of an Air-Displacement Micropipette

Typical components include:
- Plunger button
- Volume adjustment dial
- Digital volume display
- Tip ejector button
- Shaft
- Disposable pipette tip holder
Disposable tips ensure sterility and prevent cross-contamination between samples.
Types of Air-Displacement Micropipettes
Air-displacement micropipettes are available in several configurations:
- Fixed volume micropipette – single preset volume
- Variable volume micropipette – adjustable range
- Single-channel pipette – one sample at a time
- Multi-channel pipette – multiple samples simultaneously
- Manual micropipette
- Electronic micropipette
Air-Displacement Micropipette Manufacturer – Labolit

Labolit is a leading micropipette manufacturer, laboratory instrument manufacturer, and scientific equipment supplier providing high-precision air-displacement micropipettes for laboratories across India and worldwide.
Key Features of Labolit Air-Displacement Micropipettes
- High accuracy and calibration stability
- Fixed and variable volume models
- Ergonomic lightweight design
- Autoclavable components
- Compatible with universal pipette tips
- Ideal for research, PCR, IVF, diagnostics, and microbiology laboratories
Common Volume Ranges
- 0.5–10 µL
- 2–20 µL
- 20–200 µL
- 100–1000 µL
- 1–10 mL
✅ Best Air-Displacement Micropipette Manufacturer – Labolit
Labolit manufactures premium quality micropipettes, pipettes, laboratory instruments, and scientific equipment designed for high precision liquid handling in modern laboratories.
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